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ZAR1/2‐Regulated Epigenetic Modifications are Essential for Age‐Associated Oocyte Quality Maintenance and Zygotic Activation

Abstract The developmental competence and epigenetic progression of oocytes gradually become dysregulated with increasing maternal age. However, the mechanisms underlying age‐related epigenetic regulation in oocytes remain poorly understood. Zygote arrest proteins 1 and 2 (ZAR1/2) are two maternal f...

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Príomhchruthaitheoirí: Yan Rong, Yu‐Ke Wu, Yingyan Chen, Qing Liu, Leilei Ai, Yun‐Wen Wu, Yezhang Zhu, Yin‐Li Zhang, Chengkan Liu, Yerong Ma, Xiaomei Tong, Jiamin Jin, Xiaoxuan Li, Yan Zhou, Shu‐Yan Ji, Songying Zhang, Heng‐Yu Fan
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Wiley 2025-02-01
Sraith:Advanced Science
Ábhair:
Rochtain ar líne:https://doi.org/10.1002/advs.202410305
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