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pHLIP-fused PD-L1 engages avelumab to elicit NK cytotoxicity under acidic conditions

Natural killer (NK) cells represent key player in immune surveillance to eliminate transformed or malignant cells. One of mechanisms of action of NK cells is antibody-dependent cell-mediated cytotoxicity (ADCC) by recognizing tumor antigens on the surface of cancer cells. However, the heterogeneity...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Junjuan Feng, Hang Zheng, Yuting Zhang, Haiyan Wu, Mianjing Wang, Ying Sun, Min Zhang, He Xiao, Chunxia Qiao, Jing Wang, Longlong Luo, Xinying Li, Jiannan Feng, Yanchun Shi, Yuanqiang Zheng, Yi Wang, Dongsheng Sheng, Guojiang Chen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2024-05-01
Seri Bilgileri:Heliyon
Konular:
PD-L1
pHLIP
NK cell
Cytotoxicity
Acidic
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2405844024065824
Etiketler: Etiketle
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