Head-to-head comparison of [177Lu]Lu-FAP-2286 and [161Tb]Tb-FAP-2286 efficacy in a PDAC mouse model

Abstract Background Terbium-161 (Tb-161) emits internal conversion and Auger electrons, in addition to beta-minus radiation, which might be of added benefit for targeted radionuclide therapy (TRT) compared to Lutetium-177 (Lu-177). We extensively compared Lu-177 and Tb-161 for fibroblast activation...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Circe D. van der Heide, Carolline M. Ntihabose, Mark Konijnenberg, Hanyue Ma, Debra Stuurman, Corrina de Ridder, Yann Seimbille, Michail C. Doukas, Erik de Blois, Simone U. Dalm
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	SpringerOpen 2026-01-01
Σειρά:	EJNMMI Research
Θέματα:	Fibroblast activation protein (FAP) Cancer-associated fibroblast (CAF) Targeted radionuclide therapy (TRT) Pancreatic ductal adenocarcinoma (PDAC) Terbium-161
Διαθέσιμο Online:	https://doi.org/10.1186/s13550-026-01372-5
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!