Design, Synthesis and Preclinical Assessment of ^99mTc-iFAP for In Vivo Fibroblast Activation Protein (FAP) Imaging

Fibroblast activation protein (FAP) is expressed in the microenvironment of most human epithelial tumors. ⁶⁸Ga-labeled FAP inhibitors based on the cyanopyrrolidine structure (FAPI) are currently used for the detection of the tumor microenvironment by PET imaging. This research aimed to de...

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Bibliografski detalji

Glavni autori:	Diana Trujillo-Benítez, Myrna Luna-Gutiérrez, Guillermina Ferro-Flores, Blanca Ocampo-García, Clara Santos-Cuevas, Gerardo Bravo-Villegas, Enrique Morales-Ávila, Pedro Cruz-Nova, Lorenza Díaz-Nieto, Janice García-Quiroz, Erika Azorín-Vega, Antonio Rosato, Laura Meléndez-Alafort
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2022-01-01
Serija:	Molecules
Teme:	fibroblast activation protein FAP inhibitors technetium-99m HYNIC-iFAP
Online pristup:	https://www.mdpi.com/1420-3049/27/1/264
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