Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL
Abstract For children and young adults with T-lineage acute lymphoblastic leukemia (T-ALL), event free survival following relapse is < 10%. We recently showed that rearrangements of the mixed lineage leukemia gene (KMT2A-R) are associated with induction failure and an inferior survival in T-ALL. Bec...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2018-08-01
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| Serie: | Biomarker Research |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s40364-018-0141-z |
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