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Long non-coding RNA HCAR promotes endochondral bone repair by upregulating VEGF and MMP13 in hypertrophic chondrocyte through sponging miR-15b-5p

Endochondral bone formation is an important route for bone repair. Although emerging evidence has revealed the functions of long non-coding RNAs (lncRNAs) in bone and cartilage development, the effect of lncRNAs in endochondral bone repair is still largely unknown. Here, we identified a lncRNA, name...

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Principais autores: Yun Bai, Xiaoshan Gong, Rui Dong, Zhen Cao, Ce Dou, Chuan Liu, Jianmei Li, Fei Kang, Jingjin Dai, Chunrong Zhao, Zhansong Tian, Jiulin Tan, Qijie Dai, Shiwu Dong
Format: Artigo
Sprog:Inglês
Udgivet: KeAi Communications Co., Ltd. 2022-03-01
Serier:Genes and Diseases
Fag:
Bone marrow mesenchymal stem cells
Bone repair
Chondrocyte
Enchondral bone repair
Long non coding RNA
Online adgang:http://www.sciencedirect.com/science/article/pii/S2352304220300969
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