Transient Early Mechanical Loading Induces Hypertrophic Chondrocyte Differentiation of Human Mesenchymal Stromal Cells

Optimal mechanical parameters for successful bone-healing remain unclear despite their critical influence on fracture outcomes, and the timing of post-surgery mobilization is still controversial despite many clinical observations and pre-clinical studies. In this bioreactor in vitro work, we investi...

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Detalhes bibliográficos

Principais autores:	Sina Enzmann, Aline N. Klaus, Romano Matthys, Esther Wehrle, Martin J. Stoddart, Sophie Verrier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-11-01
coleção:	Cells
Assuntos:	human MSC mechanical strain hypertrophic chondrocytes in vitro 3D bioreactor
Acesso em linha:	https://www.mdpi.com/2073-4409/14/22/1773
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