Transient Early Mechanical Loading Induces Hypertrophic Chondrocyte Differentiation of Human Mesenchymal Stromal Cells

Optimal mechanical parameters for successful bone-healing remain unclear despite their critical influence on fracture outcomes, and the timing of post-surgery mobilization is still controversial despite many clinical observations and pre-clinical studies. In this bioreactor in vitro work, we investi...

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Autors principals:	Sina Enzmann, Aline N. Klaus, Romano Matthys, Esther Wehrle, Martin J. Stoddart, Sophie Verrier
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-11-01
Col·lecció:	Cells
Matèries:	human MSC mechanical strain hypertrophic chondrocytes in vitro 3D bioreactor
Accés en línia:	https://www.mdpi.com/2073-4409/14/22/1773
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