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Mechanobiology of hypertrophic chondrocyte mineralization: Biomechanical regulation and therapeutic implications in skeletal disorders

Chondrocyte proliferation, differentiation and hypertrophic mineralization are central events that guide subsequent vascular invasion and bone replacement processes. This process is controlled by a sophisticated molecular network including transcription factors such as SOX9 and Runx2, as well as key...

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Principais autores: Yuhao Liu, Guangyu Xu, Yi Shen, Shaotian Fu, An Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-06-01
Colecção:Mechanobiology in Medicine
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Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2949907026000239
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