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An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro

A crucial issue for Treg-based immunotherapy is to maintain a bona fide Treg phenotype as well as suppressive function during and after ex vivo expansion. Several strategies have been applied to harness Treg lineage stability. For instance, CD28 superagonist stimulation in vitro, in the absence of C...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Paulo C. M. Urbano, Hans J. P. M. Koenen, Irma Joosten, Xuehui He
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2018-03-01
Rangatū:Frontiers in Immunology
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00573/full
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