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Polyamine Depletion Attenuates Isoproterenol-Induced Hypertrophy and Endoplasmic Reticulum Stress in Cardiomyocytes

Background/Aim: Polyamines (putrescine, spermidine and spermine) play an essential role in cell growth, differentiation and apoptosis. Hypertrophy is accompanied by an increase in polyamine synthesis and endoplasmic reticulum stress (ERS) in cardiomyocytes. The present study was undertaken to elucid...

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Auteurs principaux: Yan Lin, Xiaojie Zhang, Lina Wang, Yajun Zhao, Hongzhu Li, Wei Xiao, Changqing Xu, Jicheng Liu
Format: Artigo
Langue:Inglês
Publié: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Collection:Cellular Physiology and Biochemistry
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Accès en ligne:http://www.karger.com/Article/FullText/366350
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