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Endoplasmic reticulum stress mediates homocysteine-induced hypertrophy of cardiac cells through activation of cyclic nucleotide phosphodiesterase 1C

Although the association of elevated homocysteine level with cardiac hypertrophy has been reported, the molecular mechanisms by which homocysteine induces cardiac hypertrophy remain inadequately understood. In this study we aim to uncover the roles of cyclic nucleotide phosphodiesterase 1 (PDE1) and...

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Principais autores: Sun Wentao, Zhou Yang, Xue Hongmei, Hou Haitao, He Guowei, Yang Qin
Formato: Artigo
Idioma:Inglês
Publicado em: China Science Publishing & Media Ltd. 2022-02-01
coleção:Acta Biochimica et Biophysica Sinica
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Acesso em linha:https://www.sciengine.com/doi/10.3724/abbs.2022009
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