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Cryo-EM structure of the essential ribosome assembly AAA-ATPase Rix7

Rix7 is a type II AAA-ATPase that is required for the assembly of the large ribosomal subunit. Here the authors present the 4.5 Å cryo-EM structure of the Rix7 homohexamer with a polypeptide fragment bound in its central channel and provide insights into the function of Rix7 as a molecular unfoldase...

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Autori principali: Yu-Hua Lo, Mack Sobhany, Allen L. Hsu, Brittany L. Ford, Juno M. Krahn, Mario J. Borgnia, Robin E. Stanley
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2019-01-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-019-08373-0
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