Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
Many important cellular membrane fission reactions are driven by ESCRT pathways, which culminate in disassembly of ESCRT-III polymers by the AAA ATPase Vps4. We report a 4.3 Å resolution cryo-EM structure of the active Vps4 hexamer with its cofactor Vta1, ADP·BeFx, and an ESCRT-III substrate peptide...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications Ltd
2017-04-01
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| coleção: | eLife |
| Assuntos: | |
| Acesso em linha: | https://elifesciences.org/articles/24487 |
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