Drug Efflux Pump Inhibitors: A Promising Approach to Counter Multidrug Resistance in Gram-Negative Pathogens by Targeting AcrB Protein from AcrAB-TolC Multidrug Efflux Pump from <i>Escherichia coli</i>

Infections caused by multidrug resistance (MDR) of Gram-negative bacteria have become one of the most severe public health problems worldwide. The main mechanism that confers MDR to bacteria is drug efflux pumps, as they expel a wide range of compounds, especially antibiotics. Among the different ty...

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Kaituhi matua:	Rawaf Alenazy
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	MDPI AG 2022-09-01
Rangatū:	Biology
Ngā marau:	multidrug resistance drug efflux pumps inhibitors mechanisms of antibiotic resistance superfamily efflux pump RND AcrAB-TolC drug efflux complex AcrB protein
Urunga tuihono:	https://www.mdpi.com/2079-7737/11/9/1328
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!