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Drug Efflux Pump Inhibitors: A Promising Approach to Counter Multidrug Resistance in Gram-Negative Pathogens by Targeting AcrB Protein from AcrAB-TolC Multidrug Efflux Pump from <i>Escherichia coli</i>

Infections caused by multidrug resistance (MDR) of Gram-negative bacteria have become one of the most severe public health problems worldwide. The main mechanism that confers MDR to bacteria is drug efflux pumps, as they expel a wide range of compounds, especially antibiotics. Among the different ty...

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Главный автор: Rawaf Alenazy
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2022-09-01
Серии:Biology
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Online-ссылка:https://www.mdpi.com/2079-7737/11/9/1328
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