Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance
<p>Abstract</p> <p>Background</p> <p>We investigated the effects of mutations K65R and K65R plus M184V on enzymatic function and mechanisms of drug resistance in subtype C reverse transcriptase (RT).</p> <p>Methods</p> <p>Recombinant subtype C HIV-1 RTs containing K65R or K65R+M184V were purified fr...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2009-02-01
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| Серія: | Retrovirology |
| Онлайн доступ: | http://www.retrovirology.com/content/6/1/14 |
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