Comparative proteomics reveals the mechanism of cyclosporine production and mycelial growth in Tolypocladium inflatum affected by different carbon sources

Cyclosporine A (CsA) is a secondary cyclopeptide metabolite produced by Tolypocladium inflatum that is widely used clinically as an immunosuppressant. CsA production and mycelial growth differed when T. inflatum was cultured in different carbon source media. During early fermentation, CsA was prefer...

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Autors principals:	Junqi Wang, Meijie Liu, Chengzhi Mao, Sizhu Li, Jiabao Zhou, Yaqin Fan, Lizhong Guo, Hao Yu, Xiuqing Yang
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-12-01
Col·lecció:	Frontiers in Microbiology
Matèries:	Tolypocladium inflatum carbon sources fructose sucrose cyclosporine A mycelium
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1259101/full
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