Comparative proteomics reveals the mechanism of cyclosporine production and mycelial growth in Tolypocladium inflatum affected by different carbon sources

Cyclosporine A (CsA) is a secondary cyclopeptide metabolite produced by Tolypocladium inflatum that is widely used clinically as an immunosuppressant. CsA production and mycelial growth differed when T. inflatum was cultured in different carbon source media. During early fermentation, CsA was prefer...

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Bibliografische Detailangaben

Hauptverfasser:	Junqi Wang, Meijie Liu, Chengzhi Mao, Sizhu Li, Jiabao Zhou, Yaqin Fan, Lizhong Guo, Hao Yu, Xiuqing Yang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-12-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	Tolypocladium inflatum carbon sources fructose sucrose cyclosporine A mycelium
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1259101/full
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