Recent advances and expanding applications of organoid models in unveiling drug ADME profiles

Organoids are three-dimensional (3D) in vitro models generated from stem or progenitor cells that closely replicate the structural and functional complexity of human organs. These systems are emerging as powerful tools in pharmacokinetic research, addressing key limitations of traditional models suc...

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Autores principales:	Guolei Zhang, Ruifan Zhang, Zihang Shu, Jing Zhao, Lei Yin, Meiyun Shi, Yanshuo Han
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2026-06-01
Colección:	Journal of Pharmaceutical Analysis
Materias:	Organoids Pharmacokinetics ADME In vitro models Personalized medicine
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2095177926001310
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