Recent advances and expanding applications of organoid models in unveiling drug ADME profiles

Organoids are three-dimensional (3D) in vitro models generated from stem or progenitor cells that closely replicate the structural and functional complexity of human organs. These systems are emerging as powerful tools in pharmacokinetic research, addressing key limitations of traditional models suc...

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Hlavní autoři:	Guolei Zhang, Ruifan Zhang, Zihang Shu, Jing Zhao, Lei Yin, Meiyun Shi, Yanshuo Han
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-06-01
Edice:	Journal of Pharmaceutical Analysis
Témata:	Organoids Pharmacokinetics ADME In vitro models Personalized medicine
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2095177926001310
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