Up-Regulation of FPR2, a Chemotactic Receptor for Amyloid β 1–42 (Aβ42), in Murine Microglial Cells by TNFα

Human FPRL1 and its mouse homologue FPR2 are functional receptors for several exogenous and host-derived chemotactic peptides, including amyloid β42 (Aβ42), a critical pathogenic factor in Alzheimer's disease. We investigated the effect of TNFα on the expression and function of FPR2 in mouse microgl...

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Bibliografische Detailangaben

Hauptverfasser:	Y.H. Cui, Y. Le, X. Zhang, W. Gong, K. Abe, R. Sun, J. Van Damme, P. Proost, J.M. Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2002-08-01
Schriftenreihe:	Neurobiology of Disease
Schlagworte:	Aβ42 chemotaxis FPR2 inflammation microglia TNFα
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0969996102905176
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