Up-Regulation of FPR2, a Chemotactic Receptor for Amyloid β 1–42 (Aβ42), in Murine Microglial Cells by TNFα
Human FPRL1 and its mouse homologue FPR2 are functional receptors for several exogenous and host-derived chemotactic peptides, including amyloid β42 (Aβ42), a critical pathogenic factor in Alzheimer's disease. We investigated the effect of TNFα on the expression and function of FPR2 in mouse microgl...
Sparad:
| Huvudupphov: | , , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
Elsevier
2002-08-01
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| Serie: | Neurobiology of Disease |
| Ämnen: | |
| Länkar: | http://www.sciencedirect.com/science/article/pii/S0969996102905176 |
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