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Up-Regulation of FPR2, a Chemotactic Receptor for Amyloid β 1–42 (Aβ42), in Murine Microglial Cells by TNFα

Human FPRL1 and its mouse homologue FPR2 are functional receptors for several exogenous and host-derived chemotactic peptides, including amyloid β42 (Aβ42), a critical pathogenic factor in Alzheimer's disease. We investigated the effect of TNFα on the expression and function of FPR2 in mouse microgl...

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Autors principals: Y.H. Cui, Y. Le, X. Zhang, W. Gong, K. Abe, R. Sun, J. Van Damme, P. Proost, J.M. Wang
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2002-08-01
Col·lecció:Neurobiology of Disease
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S0969996102905176
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