Hydroxyethylamine based analog targets microtubule assembly: an in silico study for anti-cancerous drug development

Abstract Microtubules are dynamic cytoskeletal structures essential for cell architecture, cellular transport, cell motility, and cell division. Due to their dynamic nature, known as dynamic instability, microtubules can spontaneously switch between phases of growth and shortening. Disruptions in mi...

全面介紹

書目詳細資料

Principais autores:	Pawan Kumar, Rajni Khan, Basant Narain Singh, Anisha Kumari, Ankit Rai, Anil Kumar Singh, Amresh Prakash, Shashikant Ray
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2024-12-01
叢編:	Scientific Reports
主題:	Αβ-tubulin MD simulation MM-GBSA
在線閱讀:	https://doi.org/10.1038/s41598-024-82823-8
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!