MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology

Abstract Background The involvement of non-neuronal cells and the cells of innate immunity has been attributed to the initiation and progression of ALS. TDP-43 pathology is observed in a broad spectrum of ALS cases and is one of the most commonly shared pathologies. The potential involvement of the...

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Autors principals:	Javier H. Jara, Mukesh Gautam, Nuran Kocak, Edward F. Xie, Qinwen Mao, Eileen H. Bigio, P. Hande Özdinler
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2019-10-01
Col·lecció:	Journal of Neuroinflammation
Matèries:	Upper motor neurons Microglia MCP1-CCR2 axis TDP-43
Accés en línia:	http://link.springer.com/article/10.1186/s12974-019-1589-y
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