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In silico structural and functional characterization of high-risk missense variants in MMP8, GZMK, and OASL genes associated with epidemic viral infections

Abstract This research explores the structural and functional consequences of high-impact missense variants in three immune-related genes MMP8 (D253N, Y261S), GZMK (A42P, L122P), and OASL (W216C) with possible relevance to host response in epidemic viral infections. A layered computational workflow...

Celý popis

Uloženo v:
Hlavní autoři: Mohamed Et-tanjaouy, Asmae Saih, Omar Machich, Abdelkrim Guendouzi, Younes Zaid, Hanaa Abdelmoumen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-03-01
Edice:Scientific Reports
Témata:
MMP8
GZMK
OASL
bioinformatic tool
SNP
gene
On-line přístup:https://doi.org/10.1038/s41598-026-40467-w
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