GNLY+CD8+ T cells bridge premature aging and persistent inflammation in people living with HIV

People living with HIV (PLWH) exhibit accelerated aging, characterized by systemic inflammation, termed “inflammaging.” While T-cell expansion is prevalent in PLWH, its connection to inflammaging remains unclear. In this study, we analyzed the TCRβ repertoire of 257 healthy controls (HC) and 228 PLW...

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Bibliografiske detaljer

Principais autores:	Hui-Fang Wang, Chao Zhang, Li-Ping Zhang, Cheng Zhen, Liang Zhao, Hui-Huang Huang, Bao-Peng Yang, Si-Yuan Chen, Wei-Zhe Li, Ming-Ju Zhou, Qian-Xi Guo, Xia Li, Bai-Lu Yin, Fang Sun, Ji-Yuan Zhang, Zhixin Zhang, Fu-Sheng Wang, Qing-Lei Zeng
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis Group 2025-12-01
Serier:	Emerging Microbes and Infections
Fag:	HIV TCR repertoire GNLY+CD8+ T cells clonal expansion inflammaging
Online adgang:	https://www.tandfonline.com/doi/10.1080/22221751.2025.2466695
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