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CD3D, GZMK, and KLRB1 Are Potential Markers for Early Diagnosis of Rheumatoid Arthritis, Especially in Anti-Citrullinated Protein Antibody-Negative Patients

Early diagnosis and monitoring of rheumatoid arthritis (RA) progress are critical for effective treatment. In clinic, the detection of rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPA) are usually combined to diagnose early RA. However, the poor specificity of RF and high heter...

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Main Authors: Junqin Lu, Yihui Bi, Yapeng Zhu, Shi Huipeng, Wenxiu Duan, Jian Zhou
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
rheumatoid arthritis
bioinformatics
biomarker
ACPA-negative
CD3D
GZMK
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.726529/full
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