क्यूआर कोड

Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis

ObjectiveActivation of Rho-GTPases in macrophages causes inflammation and severe arthritis in mice. In this study, we explore if Rho-GTPases define the joint destination of pathogenic leukocytes, the mechanism by which they perpetuate rheumatoid arthritis (RA), and how JAK inhibition mitigates these...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Eric Malmhäll-Bah, Karin M.E. Andersson, Malin C. Erlandsson, Sofia T. Silfverswärd, Rille Pullerits, Maria I. Bokarewa
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2023-08-01
श्रृंखला:Frontiers in Immunology
विषय:
Rho-GTPases
CD14+ cells
synovia
arthritis
oxidative phosphorylation
proteasome
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1187093/full
टैग: टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन