Prognostic and immunological significance of key gluconeogenesis regulators, PCK1 and PCK2, in human cancers especially kidney renal clear cell carcinoma: Insights from pan-cancer analysis, PCKs signature construction, and in vitro experiments
Background: Metabolic reprogramming is a significant feature of tumor cells, and targeting metabolic pathways has become a viable strategy for cancer therapy. Gluconeogenesis is essential to glucose metabolism, with phosphoenolpyruvate carboxykinase 1 (PCK1) and phosphoenolpyruvate carboxykinase 2 (...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2023-09-01
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| Серии: | Journal of Radiation Research and Applied Sciences |
| Предметы: | |
| Online-ссылка: | http://www.sciencedirect.com/science/article/pii/S1687850723000924 |
| Метки: |
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