Prognostic and immunological significance of key gluconeogenesis regulators, PCK1 and PCK2, in human cancers especially kidney renal clear cell carcinoma: Insights from pan-cancer analysis, PCKs signature construction, and in vitro experiments
Background: Metabolic reprogramming is a significant feature of tumor cells, and targeting metabolic pathways has become a viable strategy for cancer therapy. Gluconeogenesis is essential to glucose metabolism, with phosphoenolpyruvate carboxykinase 1 (PCK1) and phosphoenolpyruvate carboxykinase 2 (...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2023-09-01
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| Col·lecció: | Journal of Radiation Research and Applied Sciences |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S1687850723000924 |
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