CRISPR/Cas9-mediated generation of a homozygous CRB2 knockout H1 human embryonic stem cell line
Mutations in the Crumbs homolog 2 (CRB2) gene cause various autosomal recessive genetic diseases, such as leber congenital amaurosis, retinitis pigmentosa and ventriculomegaly with cystic kidney disease. However, the precise roles of CRB2 in cell fate determination remains unknown. Here, we generate...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2025-04-01
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| シリーズ: | Stem Cell Research |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S1873506125000273 |
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