Generation of an RNF1-deficient human pluripotent stem cell line using CRISPR/Cas9 technology
RNF1 (RING1A) is a catalytic component of the polycomb repressive complex 1 (PRC1) involved in regulation of, among others, embryonic development and disease progression. However, the exact role of RNF1 in self-renewal and differentiation of human embryonic stem cells (ESCs) remains unknown. Here, w...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2022-07-01
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| coleção: | Stem Cell Research |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S1873506122001581 |
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