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Antiplatelet Agents Affecting GPCR Signaling Implicated in Tumor Metastasis

Metastasis requires that cancer cells survive in the circulation, colonize distant organs, and grow. Despite platelets being central contributors to hemostasis, leukocyte trafficking during inflammation, and vessel stability maintenance, there is significant evidence to support their essential role...

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Principais autores: Gianenrico Rovati, Annalisa Contursi, Annalisa Bruno, Stefania Tacconelli, Patrizia Ballerini, Paola Patrignani
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Cells
Fag:
cancer metastasis
G protein-coupled receptors
epithelial–mesenchymal transition
platelets
cyclooxygenases
P2Y12 antagonists
Online adgang:https://www.mdpi.com/2073-4409/11/4/725
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