Optimizing aspirin dose for colorectal cancer patients through deep phenotyping using novel biomarkers of drug action

Background: Low-dose aspirin’s mechanism of action for preventing colorectal cancer (CRC) is still debated, and the optimal dose remains uncertain. We aimed to optimize the aspirin dose for cancer prevention in CRC patients through deep phenotyping using innovative biomarkers for aspirin’s action.Me...

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Hlavní autoři:	Paola Patrignani, Stefania Tacconelli, Annalisa Contursi, Elena Piazuelo, Annalisa Bruno, Stefania Nobili, Matteo Mazzei, Cristina Milillo, Ulrika Hofling, Gonzalo Hijos-Mallada, Carlos Sostres, Angel Lanas
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-02-01
Edice:	Frontiers in Pharmacology
Témata:	colorectal cancer biomarker-based aspirin dose optimization thromboxane A2 prostaglandin E2 cyclooxygenases platelets
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1362217/full
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