Glycyrrhetinic Acid-Functionalized Mesoporous Silica Nanoparticles for the Co-Delivery of DOX/CPT-PEG for Targeting HepG2 Cells

A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles were decorated with glycyrrhetinic acid (GA) to target HepG2 cells. The highly insoluble CPT w...

Full beskrivning

Bibliografiska uppgifter

Huvudupphov:	Gabriel Martínez-Edo, Cristina Fornaguera, Salvador Borrós, David Sánchez-García
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	MDPI AG 2020-11-01
Serie:	Pharmaceutics
Ämnen:	mesoporous silica nanoparticles dual release doxorubicin camptothecin anticancer drugs combination therapy
Länkar:	https://www.mdpi.com/1999-4923/12/11/1048
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!