Glycyrrhetinic Acid-Functionalized Mesoporous Silica Nanoparticles for the Co-Delivery of DOX/CPT-PEG for Targeting HepG2 Cells

A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles were decorated with glycyrrhetinic acid (GA) to target HepG2 cells. The highly insoluble CPT w...

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Principais autores:	Gabriel Martínez-Edo, Cristina Fornaguera, Salvador Borrós, David Sánchez-García
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2020-11-01
叢編:	Pharmaceutics
主題:	mesoporous silica nanoparticles dual release doxorubicin camptothecin anticancer drugs combination therapy
在線閱讀:	https://www.mdpi.com/1999-4923/12/11/1048
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