Uptake of L-cystine via an ABC transporter contributes defense of oxidative stress in the L-cystine export-dependent manner in Escherichia coli.

Intracellular thiols like L-cystine and L-cystine play a critical role in the regulation of cellular processes. Here we show that Escherichia coli has two L-cystine transporters, the symporter YdjN and the ATP-binding cassette importer FliY-YecSC. These proteins import L-cystine, an oxidized product...

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Auteurs principaux:	Iwao Ohtsu, Yusuke Kawano, Marina Suzuki, Susumu Morigasaki, Kyohei Saiki, Shunsuke Yamazaki, Gen Nonaka, Hiroshi Takagi
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2015-01-01
Collection:	PLoS ONE
Accès en ligne:	http://europepmc.org/articles/PMC4383340?pdf=render
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