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S-Sulfocysteine Induces Seizure-Like Behaviors in Zebrafish

Sulfite is a neurotoxin, which is detoxified by the molybdenum cofactor (Moco)-dependent enzyme sulfite oxidase (SOX). In humans, SOX deficiency causes the formation of the glutamate analog S-Sulfocysteine (SSC) resulting in a constant overstimulation of ionotropic glutamatergic receptors. Overstimu...

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Bibliografske podrobnosti
Principais autores: Jennifer Plate, Wiebke A. Sassen, Ahmed H. Hassan, Franziska Lehne, Reinhard W. Köster, Tobias Kruse
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019-04-01
Serija:Frontiers in Pharmacology
Teme:
Online dostop:https://www.frontiersin.org/article/10.3389/fphar.2019.00122/full
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