Amyloid beta accumulations and enhanced neuronal differentiation in cerebral organoids of Dutch-type cerebral amyloid angiopathy patients

IntroductionADutch-type cerebral amyloid angiopathy (D-CAA) is a hereditary brain disorder caused by a point mutation in the amyloid precursor protein (APP) gene. The mutation is located within the amyloid beta (Aβ) domain of APP and leads to Aβ peptide accumulation in and around the cerebral vascul...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Elena Daoutsali, Barry A. Pepers, Stavros Stamatakis, Linda M. van der Graaf, Gisela M. Terwindt, David A. Parfitt, Ronald A. M. Buijsen, Willeke M. C. van Roon-Mom
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2023-01-01
سلاسل:	Frontiers in Aging Neuroscience
الموضوعات:	in vitro 3D disease modeling cerebral organoids Dutch-type cerebral amyloid angiopathy Aβ accumulations astrocytes
الوصول للمادة أونلاين:	https://www.frontiersin.org/articles/10.3389/fnagi.2022.1048584/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!