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Coupled binding mechanism of three sodium ions and aspartate in the glutamate transporter homologue GltTk

In neurons and glia, glutamate transporters catalyse the reuptake of this neurotransmitter by coupling it with cation transport. Here the authors combine X-ray crystallography and molecular dynamics simulations of the archeal glutamate transporter GltTkto get insight into the coupled transport mecha...

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Principais autores: Albert Guskov, Sonja Jensen, Ignacio Faustino, Siewert J. Marrink, Dirk Jan Slotboom
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2016-11-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/ncomms13420
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