BH3-only protein expression determines hepatocellular carcinoma response to sorafenib-based treatment

Abstract Hepatocellular carcinoma (HCC) represents a global health challenge with limited therapeutic options. Anti-angiogenic immune checkpoint inhibitor-based combination therapy has been introduced for progressed HCC, but improves survival only in a subset of HCC patients. Tyrosine-kinase inhibit...

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Bibliografiske detaljer

Principais autores:	Stephanie Busche, Katharina John, Franziska Wandrer, Florian W. R. Vondran, Ulrich Lehmann, Heiner Wedemeyer, Frank Essmann, Klaus Schulze-Osthoff, Heike Bantel
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2021-07-01
Serier:	Cell Death and Disease
Online adgang:	https://doi.org/10.1038/s41419-021-04020-z
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