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Difference in F-Actin Depolymerization Induced by Toxin B from the Clostridium difficile Strain VPI 10463 and Toxin B from the Variant Clostridium difficile Serotype F Strain 1470

Clostridium difficile toxin A (TcdA) and toxin B (TcdB) are the causative agent of the C. difficile-associated diarrhea (CDAD) and its severe form, the pseudomembranous colitis (PMC). TcdB from the C. difficile strain VPI10463 mono-glucosylates (thereby inactivates) the small GTPases Rho, Rac, and C...

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書目詳細資料
Principais autores: Harald Genth, Micro Müller, Tianbang Wang, Martin May
格式: Artigo
語言:Inglês
出版: MDPI AG 2013-01-01
叢編:Toxins
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在線閱讀:http://www.mdpi.com/2072-6651/5/1/106
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