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Amino Imidate Catalyzed Asymmetric Michael Reactions of Ketones and Nitroalkenes

The efficiency of an amino imidate organocatalyst was evaluated in the Michael reaction of ketones with nitroalkenes. tert-Butyl­ l-proline imidate was found to be a syn-selective catalyst, generating products with moderate to good enantioselectivities of up to 84% ee. The best substrates were found...

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Autores principales: Bohdan Sosunovych, Alexander J. Brown, Paul A. Clarke
Formato: Artigo
Lenguaje:Inglês
Publicado: Georg Thieme Verlag KG 2022-02-01
Colección:SynOpen
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Acceso en línea:http://www.thieme-connect.de/DOI/DOI?10.1055/a-1761-4495
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