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Asymmetric organocatalytic Michael addition of cyclopentane-1,2-dione to alkylidene oxindole

An asymmetric Michael reaction between cyclopentane-1,2-dione and alkylidene oxindole was studied in the presence of a multifunctional squaramide catalyst. Michael adducts were obtained in high enantioselectivities and in moderate diastereoselectivities.

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Autori principali: Estelle Silm, Ivar Järving, Tõnis Kanger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2022-02-01
Serie:Beilstein Journal of Organic Chemistry
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Accesso online:https://doi.org/10.3762/bjoc.18.18
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