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Hexaraphane as a potential therapeutic strategy for tauopathies

Alzheimer's disease (AD) is characterized by pathological hyperphosphorylation of TAU protein, leading to neurofibrillary tangle formation, synaptic dysfunction, neuroinflammation, and neuronal loss. Hexaraphane (6-(methylsulfinyl) hexyl isothiocyanate; HXN), a bioactive compound derived from Wasabi...

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Detalles Bibliográficos
Principais autores: Ángel Juan García-Yagüe, Daniel Carnicero-Senabre, Ángel Núñez, Raffaela Cipriani, Estibaliz Capetillo-Zarate, Maribel Escoll, Isao Okunishi, Ana I. Rojo, Antonio Cuadrado
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2026-05-01
Series:Redox Biology
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2213231726001059
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