Disease pathogenicity in Hutchinson–Gilford progeria syndrome mice: insights from lung-associated alterations

Abstract Background Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by accelerated aging, impaired growth, disrupted lipid metabolism, and reduced lifespan. Methods Prior research has primarily focused on cardiovascular manifestations, our research sheds light on...

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Detalhes bibliográficos

Principais autores:	Jingjing Wang, Yuelin Guan, Yue Wang, Junyi Tan, Zhongkai Cao, Yuhan Ding, Langping Gao, Haidong Fu, Xiangjun Chen, Jianyu Lin, Ning Shen, Xudong Fu, Fangqin Wang, Jianhua Mao, Lidan Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-03-01
coleção:	Molecular Medicine
Assuntos:	Aging Hutchinson–Gilford progeria syndrome Lungs Progerin Rare diseases
Acesso em linha:	https://doi.org/10.1186/s10020-025-01165-x
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