Disease pathogenicity in Hutchinson–Gilford progeria syndrome mice: insights from lung-associated alterations

Abstract Background Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by accelerated aging, impaired growth, disrupted lipid metabolism, and reduced lifespan. Methods Prior research has primarily focused on cardiovascular manifestations, our research sheds light on...

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主要な著者:	Jingjing Wang, Yuelin Guan, Yue Wang, Junyi Tan, Zhongkai Cao, Yuhan Ding, Langping Gao, Haidong Fu, Xiangjun Chen, Jianyu Lin, Ning Shen, Xudong Fu, Fangqin Wang, Jianhua Mao, Lidan Hu
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-03-01
シリーズ:	Molecular Medicine
主題:	Aging Hutchinson–Gilford progeria syndrome Lungs Progerin Rare diseases
オンライン･アクセス:	https://doi.org/10.1186/s10020-025-01165-x
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