TRH and TRH-like peptide levels covary with caloric restriction and oral metformin in rat heart and testis
Background: Obesity, type 2 diabetes, and major depression are common comorbidities in aging populations. Metformin (MF) mimics effects of caloric restriction (CR) which increases health and life spans. CR suppresses central TRH activity resulting in bradycardia and suppression of energy expenditure...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2022-06-01
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| Col·lecció: | Endocrine and Metabolic Science |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S2666396122000048 |
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